Methylated Vitamin B12 5000mcg Spray as Methylcobalamin | Igennus

Name: Super B12-Complex 5000mcg Sublingual Spray, Methylated Vitamin B12 as Methylcobalamin, Sugar-Free & Natural Cherry Flavour, Vegan
Rating: 4.92 (13 reviews)

Igennus Super B12-Complex spray and packaging on a white background

Super B12-Complex 5000mcg Sublingual Spray, Methylated Vitamin B12 as Methylcobalamin, Sugar-Free & Natural Cherry Flavour, Vegan

45 servings

£19.99

Super B12-Complex 5000mcg Sublingual Spray, Methylated Vitamin B12 as Methylcobalamin, Sugar-Free & Natural Cherry Flavour, Vegan

£19.99

Great for: high-intensity support for increasing vitamin B12 levels to support energy production & metabolism, psychological function and red blood cell production

Super B12-Complex 5000mcg Spray has been expertly formulated to effectively raise cellular levels of this essential nutrient. The superior sublingual format delivers vitamin B12 directly into the bloodstream, bypassing gut absorption challenges. With a natural cherry flavour, Super B12-Complex is pleasant and easy to use.

Unfortunately, Super B12-Complex 5000mcg Sublingual Spray is not available to order in Europe. We apologise for any inconvenience caused.

Real use & expert insights

Each bottle contains 90 sprays/45 servings.

Adults: Spray once under the tongue and delay swallowing before repeating. Do not exceed the stated dose. Replace lid after use.

This product should not be used as a substitute for a varied and balanced diet and healthy lifestyle. Seek professional medical advice before taking any food supplement if you are pregnant or breastfeeding, or are taking medication. Keep out of the reach of children. Store in a cool, dry place and away from sunlight.

Ingredients: Water; sweetener: xylitol; vitamin B12 (as methylcobalamin, adenosylcobalamin & hydroxocobalamin); natural flavouring (cherry); acidity regulator: citric acid; preservative: potassium sorbate

Nutrient	Per 2 sprays	% NRV*
Vitamin B12	5000 µg	200000
of which methylcobalamin	1667 µg	66667
of which adenosylcobalamin	1667 µg	66667
of which hydroxocobalamin	1667 µg	66667

*% Nutrient Reference Value

This product is not made with any ingredients containing gluten, wheat, dairy, soya, eggs, fish, shellfish, tree nuts or peanuts. Our manufacturing facilities have strict allergen management procedures in place, however we cannot guarantee that our products are made in allergen-free facilities without the very small risk of trace amounts of cross contamination.

No sugar, artificial colours, flavours or sweeteners; not tested on animals; non-GMO; suitable for vegetarians & vegans; compatible with halal & kosher diets.

We often get asked many questions about our products, so our nutritionists have compiled this downloadable product information guide to ensure you get the most from taking Super B12-Complex 5000mcg Spray. Find out when to take it, at what dose and how to maximise absorption for optimum results.

Sublingual delivery bypasses gastrointestinal absorption pathways and effectively raises vitamin B12 status:

Chan, C. et al. Oral Vitamin B12 Replacement for the Treatment of Pernicious Anemia. Front Med (Lausanne). 2016 Aug 23;3:38
Del Bo’, C. et al. Effect of two different sublingual dosages of vitamin B12 on cobalamin nutritional status in vegans and vegetarians with a marginal deficiency: A randomized controlled trial. Clin Nutr. 2019 Apr;38(2):575-583
Delpre, G. et al. Sublingual therapy for cobalamin deficiency as an alternative to oral and parenteral cobalamin supplementation. Lancet. 1999;354(9180):740–1
Smith, T. and Johnson, M. Sublingual delivery of micronutrients: Mechanisms and clinical implications. Nutr Health. 2020;26(2):85–92

Combining multiple forms of vitamin B12 may support broader tissue delivery and utilisation compared to single-form B12 supplements:

Adams, J.F. et al. Absorption of cyanocobalamin, coenzyme B₁₂, methylcobalamin, and hydroxocobalamin at different dose levels. Scand J Gastroenterol. 1971;6(3):249-52
Kelly, G. The coenzyme forms of vitamin B12: Toward an understanding of their therapeutic potential. Alt Med Rev. 1997;2(6):459-471
Paul, C. and Brady, D.M. Comparative Bioavailability and Utilisation of Particular Forms of B12 Supplements With Potential to Mitigate B12-Related Genetic Polymorphisms. Integr Med (Encinitas). 2017 Feb;16(1):42-49
Thakkar, K. and Billa, G. Treatment of vitamin B12 deficiency – methylcobalamin? Cyanocobalamin? Hydroxocobalamin? - clearing the confusion. Eur J Clin Nutr. 2015 Jan;69(1):1-2

Different forms of vitamin B12 may help overcome variations in absorption and metabolism associated with common genetic polymorphisms:

Paul, C. and Brady, D.M. Comparative Bioavailability and Utilisation of Particular Forms of B12 Supplements With Potential to Mitigate B12-Related Genetic Polymorphisms. Integr Med (Encinitas). 2017 Feb;16(1):42-49
Surendran, S. et al. An update on vitamin B12-related gene polymorphisms and B12 status. Genes Nutr. 2018 Feb 6;13:2

SUPER STRENGTH 5000 mcg -

delivers a potent dose of vitamin B12 from 2 sprays; for enhanced uptake, spray once under the tongue and delay swallowing before repeating

SUPERIOR ABSORPTION -

sublingual delivery boosts absorption by delivering vitamin B12 directly into the bloodstream via passive diffusion under the tongue, bypassing absorption challenges in the gut

THREE BIOACTIVE B12 FORM -

we provide naturally occurring and bioactive forms of B12 – methylated B12 as methylcobalamin, plus adenosylcobalamin & hydroxocobalamin (no synthetic cyanocobalamin) to achieve higher B12 uptake

SUPPORTS ENERGY LEVELS -

this B12 spray is ideal for reducing tiredness and fatigue as it contributes to normal red blood cell formation and energy-yielding metabolism

PURE & CLEAN -

we use hypoallergenic ingredients with no unnecessary additives; UK GMP-manufactured, certified vegan, non-GMO & compatible with halal and kosher diets

Vitamin spray with cherry flavor packaging, surrounded by cherries and a bowl of cereal.

Supplement spray bottle with packaging on a table with a bowl of fruit and a plant in the background.

Super B12-Complex has been expertly formulated to effectively raise cellular levels of this essential nutrient. The superior sublingual format delivers vitamin B12 directly to the bloodstream, bypassing absorption challenges in the gut. With a natural cherry flavour, Super B12-Complex is pleasant and easy to use. This formula contains natural flavours and sweeteners, and no sugar, colours or unpleasant additives.

Infographic detailing an advanced vitamin B12 formula with three bioactive forms on a light background.

Infographic detailing advanced vitamin B12 formula with three bioactive forms on a light background.

Different forms of B12 are required for different functions in the body, so we provide three naturally occurring and bioactive forms – methylated methylcobalamin, plus adenosylcobalamin and hydroxocobalamin - for greater health coverage.

Close-up of a person's hands holding their stomach with a white background

Enhanced absorption bypasses the gut

Standard absorption of vitamin B12 via the gut relies on several factors that can easily be compromised, and is limited to small quantities of B12 at any one time. Absorption is usually reliant on adequate stomach acid to detach B12 from proteins in the diet, and the presence of intrinsic factor (IF) - a binding protein which supports absorption in the intestines. Levels of stomach acid and IF are often reduced by medication, genetic variations, digestive disorders and ageing, leading to reduced B12 uptake.

Illustration of a mouth with teeth on a blue background

High strength & sublingual delivery

We use the superior sublingual format to bypass the digestive system, avoiding any absorption issues which may be present. Sublingual delivery allows vitamin B12 to be absorbed directly into the bloodstream via passive diffusion under the tongue. This superior uptake mechanism is ideal for those who may have suboptimal digestion. 2 sprays deliver a potent dose of 5000mcg B12, ideal for supporting B12 levels.

Illustration of methylcobalamin, adenosylcobalamin, and hydroxocobalamin with a blue background.

Three superior forms of B12

Standard B12 supplements often deliver a single form of B12 as synthetic cyanocobalamin, a poorly absorbed form. To provide superior bioavailability and retention, we combine three naturally occurring and bioactive forms - methylcobalamin, adenosylcobalamin and hydroxocobalamin. These forms of B12 are also required for different functions in the body, offering greater health coverage. Those with genetic variations may also benefit from taking multiple forms to raise B12 status more efficiently.

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Energy production

Adenosylcobalamin is an active form of B12 found in cellular tissues and retained in mitochondria - the powerhouse of cells - where it supports cellular energy production. Adenosylcobalamin also accounts for ~60-70% of total B12 stored in the liver. With co-factor activity, this form also supports brain development and growth. Similar to methylcobalamin, adenosylcobalamin has superior bioavailability with the advantage of delivering B12 more efficiently to cells.

Mood balance

Active predominantly in blood plasma, methylcobalamin is required to convert folic acid to its active form. Providing superior bioavailability, methylcobalamin is also a cofactor for homocysteine recycling, essential for neurotransmitter function, affecting brain function and mood balance. With an important role in detoxification, methylcobalamin also supports the formation of S-adenosylmethionine (SAMe), a universal methyl donor for almost 100 different substrates, including DNA, RNA, hormones, proteins, and lipids.

Close-up of three red strawberries on a green plant with a blurred green background

Red blood cell production

Hydroxocobalamin is active in both cells and blood plasma. Particularly beneficial for smokers, hydroxocobalamin acts as a scavenger for detoxification by-products, including cyanide molecules and nitric oxide (NO) radicals. B12 injections often deliver B12 in the hydroxocobalamin form. Vitamin B12 spray via passive diffusion under the tongue may be as efficient as B12 injections.

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Product label with purity claims, certification logos, and text about manufacturing practices on a blurred natural background.

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5 stars: 12 (92%)
4 stars: 1 (8%)
3 stars: 0 (0%)
2 stars: 0 (0%)
1 star: 0 (0%)

A wonderful spray!

A wonderful way of taking vitamin B12, especially if you don’t like taking pills. Flavour very pleasant and not sickly.
I found it easy to remember every day.
I felt more energetic in the gym - red blood cells!

20 years now no regrets just good value nutrional support

I have been using Igennus products for 20+ years and am very pleased with the quality and very confident in the positive benefits I am feeling.

For anyone with a B12 deficiency

Excellent product for anyone with a B12 deficiency. Easy and pleasant to use.

Easy to apply

Easy to apply.

B12 spray

Great flavour, easy to use and no tummy problems. I have noticed a difference in energy levels definitely less fatigue within 2 weeks. Good value too glad I chose the monthly subscription.

B12 spray

Great product. Great quantity. Great dose size and great price.
All in all its .....
Very good.

Very effective

Since starting this supplement my energy has evened out during the course of the day. It's much better than sublingual lozenges.

Very effective

This bioactive version of B12 is gentler & more effective than the sublingual tablets I've been using for years.

I love this product. The best vitamin B12 on the market.

Happy

Thanks Ingennus for the professional way you process and deliver your products. Too early to expect results but expectant! Thank you!

Love it!

Love this product. It taste good and is perfect to keep in my purse for a quick mid day energy boost!

A brilliant spray I wish I had found before

Was feeling tired had sore tongue and hair was going thin tried tablets but no improvement after two weeks of this spray the difference is great have already got my next spray for when current one runs out

Great B12 under the tongue spray

I am in my 80s and was feeling tired all the time. This spray is pleasant to take and has boosted my feeling of well-being.
A recent blood test shows my B12 levels are in the mid-range of normal, so I will continue to take this supplement.

Can this medication be used by a person who has had bariatric surgery?

Igennus Healthcare Nutrition

Good morning Angela,

Thank you for your question.

Yes, for many people who have had bariatric surgery, a vitamin B12 supplement is recommended because the surgery can reduce the body's ability to absorb vitamin B12 from food. Our Super B12-Complex 5000mcg Sublingual Spray is absorbed through the tissues of the mouth, helping to bypass many of the digestive processes that may be affected after surgery.

The spray provides methylcobalamin and adenosylcobalamin, the two biologically active forms of vitamin B12, alongside hydroxocobalamin, a naturally occurring form with a longer retention time in the body. This combination helps support healthy vitamin B12 status, energy metabolism, normal psychological function and the nervous system.

As everyone's surgery and nutritional needs are different, we always recommend following the advice of your bariatric team regarding the dose you require, and we also recommend having your vitamin B12 levels monitored regularly.

Kind regards,

Melanie Rust
Nutritional Therapist
Igennus Healthcare Nutrition

Hello, I would like to ask. Can Vitamin B12 spray be taken by a 3 year old child? In what dose can it be taken? If a 3 year old child cannot take this product, could you recommend the Vitamin B12 suitable for a 3 year old child from your products.
Thank you!

Igennus Healthcare Nutrition

Thanks for your question. There is no tolerable upper limit for vitamin B12, so it could, in theory, be used by any age group. However, the amount delivered in even one spray of Super B12-Complex 5000mcg Sublingual Spray would be a very high dose for a 3-year-old. Please discuss the dose with your doctor or healthcare professional beforehand.

Depending on the recommended dose, another product you could consider is Super B12-Complex 1000mcg Sublingual Tablets, which is still a high dose but lower than the spray. Unless the child has a particular condition, such as pernicious anaemia where they can't absorb B12 from the gastrointestinal tract, it is OK if they chew and swallow the tablet rather than waiting for it to dissolve sublingually.

If you would like more tailored advice, please feel free to get in touch with our nutrition team directly.

Kind regards,

Lara Schneider
Igennus Nutritionist

Can be given to 9 year old?

Igennus Healthcare Nutrition

Thanks for your question. There is no tolerable upper limit for vitamin B12, so Super B12-Complex 5000mcg Sublingual Spray could, in theory, be used by this age group. However, this is a very high dose for for a 9-year-old, and it is unlikely that such a high dose would be necessary.

I would suggest that, unless a doctor has specifically requested such a high dose, you could instead use Super B12-Complex 1000mcg Sublingual Tablets, which is still a high dose but considerably lower than the spray.

If you would like more tailored advice, please feel free to get in touch with our nutrition team directly.

Kind regards,

Lara Schneider
Igennus Nutritionist